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Table 1 Summary of the studies used in the systematic review and meta-analysis

From: Anemia as a risk factor for tuberculosis: a systematic review and meta-analysis

Author/year Study design Country Sample size OR/HR (95% CI) Source of population Age of participant Anemia severity
Lienhardt et al./2005# [27] Case-control West Africa 1,166 3.50* (2.57–4.79) Community Adult Mild
Lienhardt et al./2005# [27] Case-control West Africa 10.80* (6.80–17.20) Community Adult Moderate and severe
Taha et al./2011# [28] Case-control Ethiopia 809 1.87 (1.576–2.17) HIV + Adult Mild
Taha et al./2011# [28] Case-control Ethiopia 4.35 (3.97–4.72) HIV + Adult Moderate and severe
Kerkhoff et al./2014## [11] Cross-sectional S.Africa 485 2.05* (1.48–2.62) HIV + Adult Mild
Kerkhoff et al./2014## [11] Cross-sectional S.Africa 3.65* (3.16–4.12) HIV + Adult Moderate
Kerkhoff et al./2014## [11] Cross-sectional S.Africa 6.91* (6.05–7.78) HIV + Adult Severe
Pefura et al./2013 [29] Cross-sectional Cameroon 857 1.60 (1.03–2.50) PTB + Adult Not defined
Iroezindu et al./2016 [24] Cross-sectional Nigeria 339 4.50 (0.60–31.70) HIV + Adult Not defined
Beshir et al./2019 [10] Cohort Ethiopia 428 7.04 (1.03–48.15) HIV + Children Not defined
Ayalaw et al./2015 [30] Cohort Ethiopia 271 2.23 (1.19–4.15) HIV + Children Not defined
Batista et al./2013[31 Cohort Brazil 1,596 2.93 (1.86–4.62) HIV + Adult Not defined
Chu et al./2019 [17] Cohort Taiwan 109,501 1.99 (1.77–2.25) Community Adult Not defined
Alemu et al./2016 [22] Cohort Ethiopia 645 2.70 (1.60–4.50) HIV + Children Not defined
McDermid et al./2013 [32] Cohort Gambia 1,139 1.14 ** (1.02–1.27) HIV + Adult Not defined
Li et al./2013 [33] Cohort Tanzania 5,040 1.40** (1.00–1.90) HIV + Children Not defined
Enju et al./2015## [21] Cohort Tanzania 67,686 1.22 (1.13–1.33) HIV + Adult Mild
Enju et al./2015## [21] Cohort Tanzania 1.66 (1.55–1.79) HIV + Adult Moderate
Enju et al./2015## [21] Cohort Tanzania 2.03 (1.86–2.22) HIV + Adult Severe
Kerkhoff et al./2015## [20] Cohort S.Africa 1,521 0.96*(0.72–1.63) HIV+ Adult Mild
Kerkhoff et al./2015## [20] Cohort S.Africa 1.27*(0.99–1.62) HIV+ Adult Moderate
Kerkhoff et al./2015## [20] Cohort S.Africa 1.22*(0.94–1.58) HIV+ Adult Severe
Phyo et al./2019## [23] Cohort Myanmar 7,859 2.10 (1.70–2.80) HIV+ Adult Mild
Phyo et al./2019## [23] Cohort Myanmar 4.30 (3.40–5.40) HIV+ Adult Moderate
Phyo et al./2019## [23] Cohort Myanmar 4.90 (3.30–7.20) HIV+ Adult Severe
Chang et al./2015## [34] Cohort Nigeria 12,996 2.48* (2.02–3.03) HIV+ Adult Mild and moderate
Chang et al./2015## [34] Cohort Nigeria 4.36*(1.98–9.62) HIV+ Adult Severe
Choun et al./2013## [35] Cohort Cambodia 2,956 2.10 (1.40–3.30) HIV+ Adult Mild and moderate
Choun et al./2013## [35] Cohort Cambodia 3.40 (2.10–5.50) HIV+ Adult Severe
  1. NB * crude odds ratio for cross-sectional and case-control studies, and crude hazard ratio for cohort studies, **adjusted risk ratio and those without * or ** are adjusted odd ratio for cross-sectional and case-control studies, and adjusted hazard ratio for cohort studies, # the data split into two, ## the data split into three; HIV+ human immunodeficiency virus positive patients; HR hazard ratio; RR relative risk; OR odds ratio; PTB pulmonary—tuberculosis patient; S. Africa South Africa